* The report reviews key players involved
Myotonic Dystrophy therapeutics and enlists all their major and minor projects
The electromyogram revealed typical
myotonic discharges.
Myotonic dystrophy type 1 is the most common form of
myotonic muscular dystrophy diagnosed in children, with a prevalence ranging from 1 per 100,000 in Japan to 3-15 per 100,000 in Europe7.
Keywords: caregiver, dysphagia,
myotonic dystrophy, phenomenology, qualitative research
At least two of the common conditions,
myotonic dystrophy and HD, are said to occur at higher frequency in the Afrikaans-speaking population, owing to founder mutations.
This report provides comprehensive information on the therapeutic development for
Myotonic Dystrophy, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
Washington, Jan 05 ( ANI ): Researchers have revealed an atomic-level view of a genetic defect that causes a form of muscular dystrophy,
myotonic dystrophy type 2.
Myotonic dystrophy type 1 (DM1) is the most common form of adult muscular dystrophy, with an incidence of approximately 1 in 8,000.
Myotonic dystrophy type I (DM1) is caused by an expanded CTG-repeat in the 3' UTR of the DMPK gene that is quite unstable when transmitted to the next generation [35].
Mutations in splicing factors can cause diseases such as
myotonic dystrophy and cancer.
We are developing a computer model of a muscle cell based on experimentally measured parameters to find out which functional changes in the mutated channels are responsible for the
myotonic bursts.
Other chapters address mechanisms of neuropathic pain, therapeutics, carpal tunnel syndrome, cervical radiculopathy, meralgia paresthetica, Lyme radiculopathy, neuralgic amyotrophy, herpes zoster infection, polyneuropathies, inherited amyloidosis, sarcoidosis, Fabry disease, proximal
myotonic myopathy, complex regional pain syndrome, polymyalgia rheumatica, phantom pain, Brown-Sequard syndrome, syringomyelia, and headache disorders, and give information on the patient's history, clinical findings, investigations, diagnosis, and treatment.