A further study showed that IL-27 activates several IFN-inducible genes such as
myxovirus protein, oligoadenylate synthetase, RNA-dependent kinase, and apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like (APOBEC)-3G, in human monocyte-derived macrophages [123].
The rapid, disposable, in-office assay provides the interpretation of both
Myxovirus Resistance Protein A (MxA), an interferon derivative that becomes increased in the presence of acute viral infection, as well as C-reactive Protein (CRP), an acute-phase protein that is higher when bacterial infection is present.