In such cases, the megakaryocytes are present in nodal sinusoids, and they tend to stand out from the adjacent
nodal tissue because of their multilobated and hyperchromatic nuclei.
Owing to the clinical need for airway relief, an isthmusectomy and
nodal tissue sampling was performed yielding multiple portions of pink-tan fibrotic tissue weighing 45 grams and measuring 6.5 cm in greatest aggregate dimension.
INTRODUCTION: Lymph nodes are most widely distributed and easily accessible component of lymphoid tissue.(1, 2) Aspiration of lymph nodes for diagnostic purposes was first done by Griey and Gray in 1904 in patients with Sleeping sickness.(2) Enlarged palpable Cervical Lymph nodes are common and worrying presentation in adults as well as children.(3,4) Cervical Lymphadenopathy is defined as cervical lymph
nodal tissue measuring more than 1 cm.
This can be done using IHC but only a small percentage of
nodal tissue can be examined in one section.
He processes sentinel nodes individually because frozen sections waste valuable
nodal tissue. He recommends more aggressive immunohisto-chemical analysis than average, including routine HMB-45 and S100 stains and serial step sectioning through the node.
These cells were scattered throughout the
nodal tissue, but they were predominantly located in paracortical and medullary regions (Figure, B).