Quantitative assessment regarding number and diameter of chief cells and oxyphil cells and total number of cells were recorded.
Diameter of chief cells and oxyphil cells were measured under 100x objective with a horizontal eyepiece micrometre called "graticule." The graticule was calibrated with a stage micrometre.
[sup.99m]Tc-MIBI scintigraphy of parathyroid adenomas and its relation to tumour size and oxyphil cell abundance.
Preoperative localization of parathyroid lesions in hyperparathyroidism: relationship between technetium-99m-MIBI uptake and oxyphil cell content.
Calculation of average oxyphil scores: A quantitative assessment was made of the number of oxyphil cells by measuring the diameter in microns of each group of oxyphil cells in sections taken through the maximum diameter of each gland and summating the areas thus obtained by the formula [PI] ab, where 'a' & 'b' represent one half of each major & minor axis respectively, as stated by Christie A.
Comparison of oxyphil scores in male and female was done by unpaired't' test P < 0.05 was taken as statistical significance.
While most adenomas are composed of chief cells, a small percentage may be oxyphilic (>90%
oxyphils) and rare "water-clear" adenomas have also been described.
Histopathologic examination revealed that parts of the tumor contained a lobulated architecture composed of sheets, cords, and follicles of chief cells,
oxyphil cells, and clear cells; these findings were consistent with an adenoma.
Oxyphil cells in thyroid disease: a uniform change?
Neither chief nor
oxyphil cells were admixed with the WCCs.
Antibiotics disrupt the delicate ecologic balance between oxygen-loving microbes (
oxyphils) and oxygen-shunning microbes (oxyphobes).
Finally, mixtures of different cells (
oxyphils, clear cells, and chief cells) can be found in adenomas, as well as in hyperplastic glands.[3] The most important criterion is the clinical follow-up--no recurrence of hypercalcemia on long-term follow-up (at least 5 years) supports the diagnosis of adenoma.