As mentioned above, one of the approaches to improve the performance of
paper electrophoresis was to reduce adsorption of the proteins.
Is it worthwhile to pursue paper electrophoresis to the bitter end?
In 1958, Kohn published a series of 3 papers in which he reported redesigning the paper electrophoresis chamber and reducing the size of the CA membranes (21-23).
Two years later, von Klobusitzky and Konig (12), writing in a German journal, more fully described their experiments with
paper electrophoresis and the separation of a yellow pigment from snake venom-the first application of
paper electrophoresis to the separation of protein mixtures.