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para-aminosalicylic acid

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para-aminosalicylic acid

[¦par·ə ə¦me·nō¦sal·ə¦sil·ik ′as·əd]
(pharmacology)
C7H7NO3 White, crystalline drug used with other drugs in the treatment of tuberculosis. Abbreviated PAS.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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References in periodicals archive
AMK, amikacin; AMX, amoxicillin; CAP, capreomycin; CIP, ciprofloxacin; CLA, clavulanic acid; CLM, clarithromycin; CYS, cycloserine; DS, drug sensitive; DR, drug resistant; DST, drug susceptibility testing; EMB, ethambutol; EPTB, extrapulmonary tuberculosis; ETH, ethionamide; INH, isoniazid; KAN, kanamycin; LVX, levofloxacin; LZD, linezolid; mXf, moxifloxacin; OFX, ofloxacin; PAS, para-aminosalicylic acid; PTB, pulmonary tuberculosis; PZA, pyrazinamide; RIF, rifampin; STR, streptomycin; TB, tuberculosis; U, unknown; XDR TB, extensively drug- resistant tuberculosis; -, negative; +, positive.
Treatment Outcomes in Global Systematic Review and Patient Meta-Analysis of Children with Extensively Drug-Resistant Tuberculosis
Para-aminosalicylic acid, 99% purity, and zinc nitrate hexahydrate were purchased form Sigma-Aldrich.
Development of a highly biocompatible antituberculosis nanodelivery formulation based on para-aminosalicylic acid--zinc layered hydroxide nanocomposites
She was given a 7-drug regimen including ethambutol, pyrazinamide, cycloserine, para-aminosalicylic acid (PAS), and kanamycin for 18 months.
Bedaquiline and Linezolid for Extensively Drug-Resistant Tuberculosis in Pregnant Woman
Some drugs, such as capreomycin, para-aminosalicylic acid (PAS), amoxicillin-clavulanic acid and clarithromycin are reserve drugs for the management of XDR TB cases.
Drug-resistant tuberculosis in children
in December 1987, a chest radiograph obtained from one of his brothers indicated a small patchy lesion in the right upper lobe; this brother had a history of tuberculous pleural effusion in 1955 for which he was treated with isoniazid (INH), para-aminosalicylic acid, and streptomycin for an unknown duration.
Tuberculosis outbreak on Standing Rock Sioux Reservation - North Dakota and South Dakota, 1987-1990
DST was conducted for 10 drugs: rifampin (1.0 [micro]g/mL); isoniazid (0.2, 1.0, and 5.0 [micro]g/mL); ethambutol (5.0 [micro]g/mL); ofloxacin (2.0 [micro]g/mL); ciprofloxacin (2.0 [micro]g/mL); kanamycin (5.0 [micro]g/mL); capreomycin (10.0 [micro]g/mL); amikacin (4.0 [micro]g/mL); para-aminosalicylic acid (2.0 [micro]g/mL); and ethionamide (10.0 [micro]g/mL).
Additional drug resistance of multidrug-resistant tuberculosis in patients in 9 countries
The second-line companion drugs were para-aminosalicylic acid or ethionamide.
Risk factors for acquisition of drug resistance during multidrug-resistant tuberculosis treatment, Arkhangelsk Oblast, Russia, 2005-2010
On the basis of the DST results, the treatment was changed to ethambutol, pyrazinamide, amikacin, moxifloxacin, para-aminosalicylic acid, and linezolid.
Concomitant multidrug-resistant pulmonary tuberculosis and susceptible tuberculous meningitis
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