The need for Group IIA secretory
phospholipase A2 ([sPLA.sub.2]-IIA) inhibitors in inflammatory ocular disease treatment.
Lipoprotein-associated
phospholipase A2 as a novel risk marker for cardiovascular disease: a systematic review of the literature.
Quercetin as an inhibitor of snake venom secretory
phospholipase A2. Chem Biol Interac 2011; 189: 9-16, doi: 10.1016/j.cbi.2010.10.016.
Is lipoprotein-associated
phospholipase A2 activity correlated with fibrous-cap thickness and plaque volume in patients with acute coronary syndrome?
This study aimed to investigate, through molecular docking, affinity interaction of various natural phenolic compounds and some of their derivatives with
phospholipase A2, and see how this interaction occurs in order to contribute to the development of new drugs with anti-inflammatory potential.
Lipoprotein-Associated
Phospholipase A2 Activity Is Associated With Riskof Coronary Heart Disease and Ischemic Stroke.
Bickler, "Varespladib (LY315920) appears to be a potent, broad-spectrum, inhibitor of snake venom
phospholipase A2 and a possible pre-referral treatment for envenomation," Toxins, vol.
Leslie, "Protein kinase C-dependent and -independent pathways of mitogen-activated protein kinase activation in macrophages by stimuli that activate
phospholipase A2," The Journal of Biological Chemistry, vol.
Turmeric, an orange-yellow spice, widely used in curries and South Asian cuisine, is believed to reduce inflammation caused by the enzyme
phospholipase A2, which is provoked into action by pollen in your system.
It has a low molecular weight (2.85kDa) representing about 40-50% of apitoxin dry weight (GAJSKI et al., 2013; YILMAZ et al., 2016), where it synergistically acts with
phospholipase A2 (molecular weight 11kDa) which represents 11% of apitoxin dry weight (FERREIRA JUNIOR et al., 2010).