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eclampsia

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eclampsia

1. Pathol a toxic condition of unknown cause that sometimes develops in the last three months of pregnancy, characterized by high blood pressure, abnormal weight gain and convulsions
2. another name for milk fever (in cattle)
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005

eclampsia

[i′klam·sē·ə]
(medicine)
A disorder occurring during the latter half of pregnancy, characterized by elevated blood pressure, edema, proteinuria, and convulsions or coma.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Eclampsia

 

a serious disease occurring during pregnancy, labor, or the postpartum period. Eclampsia is a late stage of toxemia of pregnancy. The condition is characterized by convulsions that develop in a definite sequence. Slight fibrillar contractions of the facial muscles (15–30 seconds) are followed by tonic spasms of the total skeletal musculature and loss of consciousness (15–20 seconds). Clonic muscular spasms of the trunk and limbs occur, and, finally, the woman lapses into a brief or prolonged coma. Consciousness returns gradually. In particularly severe cases, eclampsia may occur without convulsions (comatous forms). Eclampsia is often manifested by only a few convulsions, and high blood pressure may not be a symptom. Death may occur during or after convulsions as a result of pulmonary edema, hemorrhages into the brain, and asphyxia. The fetus often dies in utero from hypoxia. The prognosis depends on the number and duration of the convulsions or on the duration of the coma.

Current treatment of eclampsia is based on principles developed by the Soviet obstetrician-gynecologist V. V. Stroganov in 1928. Total physical and mental rest is prescribed. Functioning of the vital organs is restored: Drugs are administered to decrease the excitability of the central nervous system, to lower blood pressure, and to stimulate urination. Oxygen is administered in cases of pronounced hypoxia, and labor is induced quickly but cautiously. The patient should not be moved during convulsions or while in a coma. Prompt hospitalization is required as soon as consciousness is regained. Prophylaxis includes the prevention of advanced toxemia and prompt hospital treatment of neuropathy and preeclampsia.

REFERENCE

Nikolaev, A. P. Pozdnie toksikozy beremennykh. Moscow, 1972.

A. P. KIRIUSHCHENKOV

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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References in periodicals archive
While, no statistically significant difference in Hcy levels between controls and mild pre-eclamptics was noted.
(22) demonstrated elevated maternal serum sFlt-1 levels, reduced PlGF and free VEGF levels and an up-regulation of placental Flt-1 mRNA in pre-eclamptic pregnancies.
Care-as-usual provided to formerly pre-eclamptic women in the Netherlands in the next pregnancy: Healthcare consumption, costs and maternal and child outcome.
It has been reported that in patients with underlying pre-eclamptic placental hypoxia, oxygen).
The aim of this prospective study was to examine whether there is a difference between the placentas of pre-eclamptic pregnant women and those of a control group in terms of T2* values, which are a quantitative indicator of the amount of iron and are obtained via MRI.
All pregnant women were not known hypertensive; diabetic and pre-eclamptic. Newborns of with clear congenital malformations were excluded.
(2008), the umbilical cord plasma of pre-eclamptic subjects contained large amounts of MMP9 in the form of complexes with other plasma components, and zymographic analysis demonstrated increased gelatinolytic activity at a position corresponding to MMP9 compared to control samples.
also assessed CT in pre-eclamptic pregnant women during and after pregnancy [53, 54], and they both arrived at the same conclusion: CT decreased after the parturition of pre-eclampsia puerperae.
Cardiovascular effects of aerobic exercise Training in formerly pre-eclamptic women and healthy parous control subjects.
[8] More than a quarter of our patients (29% of pre-eclamptic near-misses and 26% of near-misses with medical disease) had risk factors for hypertension in pregnancy, had an underlying medical condition but booked after 20 weeks' gestation, or had inadequate antenatal care due to noncompliance with the required antenatal visits.
Intrauterine growth restriction is a common complication of hypertensive disorders of pregnancy, and a high incidence of small for gestational age infants in pre-eclamptic women has been reported, ranging from 15% to more than 50% (1).
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