saccharin

a very sweet white crystalline slightly soluble powder used as a nonfattening sweetener. Formula: C₇H₅NO₃S

Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005

saccharin

[′sak·ə·rən]

(organic chemistry)

C₆H₄COSO₂NH A sweet-tasting, white powder, soluble in acetates, benzene, and alcohol; slightly soluble in water and ether; melts at 228°C; used as a sugar substitute for syrups, and in medicines, foods, and beverages. Also known as benzosulfimide; gluside.

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Saccharin

(also o-sulfobenzoic imide), a colorless crystalline substance with the structural formula

Saccharin is poorly soluble in water (1:250) and alcohol (1:40) and has a melting point of 228°–229°C. It is sweet but has a bitter aftertaste. The crystal hydrate of the sodium salt of saccharin, known as Crystallose, has a higher solubility in water (1:1.5).

Saccharin is obtained commercially by the oxidation of o-toluenesulfonamide. With a sweetness 400–500 times that of sugar, saccharin was formerly used in great quantities as a sugar substitute. It is not assimilated by the body but rather is excreted in the urine. Saccharin is used as a sweetener for certain items, such as toothpaste, and as an additive in electroplating technology.

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References in periodicals archive

Key words: Indian crested porcupine, Hystrix indica, zinc phosphide, grain baits, groundnut, maize, saccharin.

Testing of Groundnut - Maize Bait as Carrier of Zinc Phosphide for the Management of Indian Crested Porcupine, Hystrix indica Kerr (Rodentia: Hystricidae)

The primary aim of this paper is to present the results of SEM, XRD, PL, and Raman analysis carried out for CdO films as a function of saccharin concentration.

Physical properties of nanostructured CdO films from alkaline baths containing saccharin as additive

Regardless of the final ruling on saccharin, the FDA could make other rulings that help to open up the sweetener industry, either by allowing new uses for existing sweetener products or by allowing the use of sweeteners new to the U.S.

Sweet anticipation

Compared with nondrinkers, diet soda consumers "demonstrated more widespread activation to both saccharin and sucrose in reward-processing brain regions," the scientists say.

No-cal sodas can trick the brain: sugar-free sweeteners may contribute to obesity risk

The rats who drank the saccharin beverage ate three times the calories of those who did not.

The sweet and lowdown on sugar substitutes

Concluding that the animal studies aren't applicable to humans, the government removed saccharin from its official list of cancer-causing agents earlier this year.

How Sweet it Is

A second flavor is paired with a noncaloric US like water or saccharin. After 8 to 10 serial discrimination trials, preference for the flavor paired with the caloric solution is assessed by a two-bottle preference test or by several one-bottle tests.

The effects of naloxone on flavor-calorie preference learning indicate involvement of opioid reward systems

Saccharin consumption on Days 12 and 14 of Experiment 2 is represented in Figure 3.

Effects of swim stress on neophobia and reconditioning using a conditioned taste aversion procedure

The Environmental Protection Agency has removed the artificial sweetener saccharin and its salts from the agency's list of hazardous substances.

EPA removes Saccharin from list of hazardous substances

Like all Little Remedies products, Little Fevers contains no artificial flavors or colors and no alcohol, saccharin or gluten.

Prestige brands expands little remedies line

The complainant's name has never been released, but noted advocate of alternative medicine Andrew Weil, M.D., says, "It's hard to avoid the conclusion that the FDA's position was motivated, at least to some degree, by a desire to protect the manufacturer of aspartame (NutraSweet)." The three big FDA-approved artificial sweeteners are NutraSweet, Sweet'N Low (saccharin), and Sunette (acesulfame K).

Stevia: this sugar substitute is sweet and healthy

SACCHARIN. Discovered over a century ago, saccharin is a synthetic artificial sweetener that is 300 times sweeter than sugar.

A deluge of low-calorie sweeteners on the market, EN does the homework