Histamine H3 antagonist thioperamide dosedependently enhances memory consolidation and reverses amnesia induced by dizocilpine or
scopolamine in a one-trial inhibitory avoidance task in mice.
The findings of hole board model indicated that only aqueous Anise extract improved the memory of mice by preventing them from the damages of
scopolamine while n-hexane extract of Anise failed to do so.
Scopolamine treatment given to the control animals showed no effect on seizure susceptibility, regardless of the food deprivation duration (data not shown).
It is very interesting that
scopolamine has actually anticonvulsive effect.
Piracetam (sun pharmaceuticals),
scopolamine, normal saline, and ethanol were used.
It's similar to or the same as (accounts vary) the prescription motion sickness medication
scopolamine.
On the last day of treatment,
scopolamine (2 mg/kg) was administered as a single dose 30 min after drug administration through intraperitoneal (ip) injection route to all the groups except group I (SHAM 1).
In addition, the rat's ERP P300-like response was sensitive to pharmacological modulation of the cholinergic tone [46], which is consistent with changes observed in healthy human studies because of diminished cholinergic neurotransmission by
scopolamine or a selective muscarinic receptor antagonist [47, 48].
The company said its prescription
scopolamine 1.5 mg transdermal system patch is the AB rated generic equivalent to Transderm Scop (
scopolamine 1.5 mg).
(7) A number of NMDA antagonists have been reported to rapidly reverse--within a few hours--severe and chronic depression when administered intravenously (ketamine, rapastinel,
scopolamine), intranasally (S-ketamine), or via inhalation (nitrous oxide).
Supplemental oxygen, plus
scopolamine patches applied at least an hour prior to flight, can help too.
(2009) investigated the effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by
scopolamine. (84) The study aimed at establishing the potential therapeutic utility for DMAE p-Glu in cognitive impairments related to central cholinergic deficit.