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Sjögren's syndrome

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Sjögren's syndrome

[′shō·grənz ‚sin‚drōm]
(immunology)
An autoimmune disease characterized by the destruction of salivary and lacrimal glands, damage by T lymphocytes within the glands may be accompanied by damage by immune complexes throughout the body.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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References in periodicals archive
Pipeline Products for Sicca Syndrome (Sjogren) - Comparative Analysis 10
Global Markets Direct's, 'Sicca Syndrome (Sjogren) - Pipeline Review, H1 2016', provides an overview of the Sicca Syndrome (Sjogren) pipeline landscape.
Sjogren or sicca syndrome and serum angiotensin-converting enzyme elevation are also reported to occur in both.
It first was described by Swedish ophthalmologist Henrik Sjogren in 1933, when he noted a connection among arthritis, dry eye (keratoconjunctivitis sicca), and dry mouth (xerostomia), known as sicca syndrome (Chang, Burke, & Glass, 2010).
Less common symptoms may include Sicca Syndrome (dry eyes and mouth), cutaneous calcinosis, Raynaud's phenomenon, and dysphagia, as PBC can be associated with other autoimmune diseases such as Sjogren's syndrome and scleroderma.
The common extra-articular manifestation of RA is a dysfunction of lacrimal and salivary glands, which gradually leads to the development of sicca syndrome, respectively secondary Sjogren's syndrome (sSS) in these patients.
Results were also normal for a hypercoagulable work-up appropriate for presumed stroke in a young person: protein C, protein S, prothrombin gene mutation, Factor V Leiden, antithrombin III, antiphospholipid, homocysteine, erythrocyte sedimentation rate, C-reactive protein, antinuclear antibody, antineutrophil cytoplasmic antibody, and sicca syndrome A or B antibodies.
Finally, HCV carriers with PNALT may suffer from extrahepatic manifestations, sometimes more severe than the underlying liver disease: lymphoproliferative disorders, mixed cryoglobulinaemia, thyroid disorders, sicca syndrome, porphyria cutanea tarda, lichen planus, diabetes, chronic polyarthritis, etc.
Fibromyalgia (FM) is a chronic disorder characterized by widespread pain usually associated with other somatic and psychological symptoms including fatigue, sleep disorders, headache, anxiety, paresthesia, sicca syndrome, Raynaud's phenomenon, irritable bowel syndrome, and dysmenorrhea (1).
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