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Stereoisomerism

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The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Stereoisomerism

 

a type of isomerism characterized by different spatial arrangements of atoms in a molecule with no change in the arrangement of the bonds. Two kinds of stereoisomerism are known, namely, geometric and optical.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
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References in periodicals archive
The present study investigates the predictive role of the endogenous NOS inhibitor ADMA and its stereoisomer SDMA for cardiovascular risk, all-cause mortality, and renal function in trial patients with AASV treated in a standardized fashion according to their disease stage.
Dexmedetomidine, [4] a stereoisomer of medetomidine is a highly selective alpha 2 adrenergic agonist and has been shown to decrease anaesthetic requirements by upto 90% and to induce analgesia in rats, volunteers and patients.
The authors observed that the diastereomer ratio values in water samples were similar to those found in commercial products, which suggests recent application, since the stereoisomer degradation in the environment present a different pattern, as observed by Khazri et al.
(5) MCDA consists of two regioisomers, 2,4 and 2,6-MCDA, with four and three stereoisomers, respectively (Figure l).
Stereoisomer rearrangement processes has been well studied and documented, but limited information is published with the new olefin refrigerants which have the potential for stereoisomer rearrangement.
D-2-hydroxyglutarate and L-2-hydroxyglutarate are stereoisomers; however, they are produced through distinct biological mechanisms.
2010, 2011a, 2011b), and stereoisomer percentage in CM-HBCD, [alpha]-HBCD, [gamma]-HBCD, and CM-HBCD were individually mixed with corn oil and toluene and evaporated under vacuum; control solutions were generated using the same procedure.
Meyer eds., 1996) (collecting examples of drugs where activity is mainly associated with one stereoisomer).
Magnesium isoglycyrrhizinate (MgIG), a magnesium salt of 18[alpha]-glycyrrhizic acid stereoisomer of glycyrrhizic acid, is clinically used for the treatment of inflammatory liver diseases in China and Japan [6-8].
It acts by converting unconjugated bilirubin to more polar stereoisomer, which are less neurotoxic (cannot cross blood brain barrier) and can easily be excreted in bile and urine6.
synthetic vitamin E (dl-[alpha]-tocopherol) in feed on [alpha]-tocopherol levels, stereoisomer distribution, oxidative stress and the immune response in piglets.
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