He picks up the story with the post-war achievements of German chemists who finally discovered that the combination of an azo dye and a
sulfanilamide side chain was able to kill the family of Streptococci bacteria.
Taste of raspberries, taste of death--The 1937 elixir
sulfanilamide incident.
Ganesh, "Electrochemical detection of
sulfanilamide using pencil graphite electrode based on molecular imprinting technology," Electroanalysis, vol.
Briefly, N-(1-naphthyl)-ethylenediamine (NED) (Sigma[R], USA) was prepared at 0.1% and
sulfanilamide (Sigma[R], USA) at 1%, both with phosphoric acid at 2.5% as a diluent.
the concentration of nitrite (N[O.sub.2]), a soluble oxidation product of NO, in the culture media was measured using Gries reagent (0.1%N-l-napthylethylenediamine dihydrochloride and 1%
sulfanilamide in 5% phosphoric acid) (Ha et al., 2010).
Then,
sulfanilamide and N-1-naphtylethylenediamine dihydrochloride solutions were added to the samples, respectively.
The biopsied area was closed with surgical sutures, and cleaned with betadine topical solution and Negasunt spray (Coumaphos 30 g, Propoxur 20 g, and
Sulfanilamide 50 g/kg; Bayer Korea, Korea) and Pink spray (10 mg mercuric oxide yellow and 1 mg prednisolone/kg; Komipharm International, Siheung, Korea).
(13) Later, in response to the death of over one hundred people, mostly children, after taking elixir
sulfanilamide, the Food, Drug, and Cosmetic Act of 1938 became law.