testicular feminization
Also found in: Dictionary, Medical, Acronyms.
testicular feminization
[tes¦tik·yə·lər ‚fem·ə·nə′zā·shən] (medicine)
A hereditary disorder in which affected individuals are chromosomally XY but have a feminine phenotype and are sterile. The X-linked testicular feminization (Tfm) gene results in absent or defective testosterone receptors, leaving cells unable to bind androgens and respond even though normal male levels of androgen are present. Also known as androgen insensitivity syndrome.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive
The surgical management of incomplete
testicular feminization in three sisters.
INTRODUCTION: Androgen insensitivity (
testicular feminization) syndrome is a rare inherited form of male pseudohermaphroditism that occurs in phenotypically normal woman with adequate breast development, normal external genitalia, a vagina of variable depth, absent uterus, and sparse or absent pubic hair and axillary hair.
Inguinal hernia in females and
testicular feminization syndrome.
Copyright © 2003-2025 Farlex, Inc
Disclaimer
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.