thalassemia

[‚thal·ə′sē·mē·ə]

(medicine)

A hereditary form of hemolytic anemia resulting from a defective synthesis of hemoglobin: thalassemia major is the homozygous state accompanied by clinical illness, and thalassemia minor is the heterozygous state and may not have evident clinical manifestations. Also known as Mediterranean anemia.

The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Thalassemia

(also thalassanemia), a familial hemolytic anemia, first detected in 1925 among inhabitants of the Mediterranean region. Thalassemia is caused by disturbances in hemoglobin synthesis.

Mentioned in

References in periodicals archive

The loss of two alpha globin genes is termed alpha thalassemia minor. This condition can occur due to homozygous one-gene deletions or heterozygous two-gene deletions.

Too much [A.sub.2]--but does the patient really have beta thalassemia trait?

(a) Thalassemia minor includes [alpha]-thalassemia heterozygote, [beta]-thalassemia heterozygote, and Hb E heterozygote.

Performance Evaluation of Automated Impedance and Optical Fluorescence Platelet Counts Compared With International Reference Method in Patients With Thalassemia

Projection of population shows that a total of 647 individuals with halassemia major and 35,054 with thalassemia minor are born every year if the health and population demographics remain the same.

PROJECTION OF THALASSEMICS IN KHYBER PAKHTUNKHWA

However, there are some studies that have explored the coexistence of metabolic syndrome in patients with thalassemia minor and it has been suggested that the prevalence of metabolic syndrome showed no relationship with sex and age and these patients had just higher BMI [23].

Body composition in adult patients with thalassemia major

According to a survey above50% population of Pakistan is suffering from Thalassemia Minor and they are source of infection for

Thalassemia

Let's Be Well Red is a fantastic drive to get the point across and I am happy to be supporting it." The project, that was started by Rajvi Mehta two years ago after recovering from thalassemia minor, aims at identifying prospective anaemic women and helping them to overcome the problem by consuming an in- house manufactured ironrich bar called, GudNess.

Sameera reaches out to anaemic women

Herein, we report a case involving the coexistence of beta thalassemia minor, renal amyloidosis and FMF with the E148Q heterozygous mutation in a 46-year-old male patient with sickle cell anemia (SCA) whose abdominal pains had been attributed to sickling crisis for almost 25 years.

Secondary Amiloidosis and Familial Mediterranean fever mimicking recurrent abdominal Sickling crisis in a patient with sickle cell anemia / Orak Hucre Anemili Bir Hastada Tekrarlayan Karin Agrisi Krizini Taklit Eden Ailesel Akdeniz Atesi ve Sekonder Amiloidozis

Depending on the state of inheritance, the disorder is then known as beta thalassemia minor or thalassemia major.

Thalassemias

Validity assessment of nine descriminant functions used for the differentiation between iron deficiency anemia and thalassemia minor. J Trop Pediatr.

FREQUENCY OF IRON DEFICIENCY ANAEMIA AND BETA THALASSAEMIA TRAIT AT HAEMATOLOGY DEPARTMENT OF CHILDREN HOSPITAL, LAHORE

Thalassemia minor occurs if you receive the defective gene from only one parent.

THALASSEMIA

[1] on nitric oxide (NO) in beta thalassemia minor. in which they reached the conclusion that "These findings confirm that plasma NO levels in beta-thalassemia minor patients are decreased at the time of diagnosis." Bayraktar et al.

Nitric oxide in beta-thalassemia minor: what factors contribute?/ Beta talasemi minorde nitrik oksit: hangisi katki saglar?

Hussain inherited Thalassemia major from both parents who were diagnosed with Thalassemia minor (a mild form of anaemia).

Iraqi children look forward to a brighter future