"Recommendations based on earlier studies using a number of different tests for
vitamin D levels persist and, not surprisingly, current guidelines vary," said author Sylvia Christakos, a professor at Rutgers New Jersey Medical School.
In the meantime, Grossman says that people with low
vitamin D levels should consider supplementing it.
The researchers gave 2,000 international units of
vitamin D per day, 1 gram of marine omega-3 fatty acids, or placebo supplements to 25,871 volunteers aged 50 or older.
Vitamin D can be found naturally in only a few foods, including fatty fish (salmon, mackerel, sardines, and cod liver oil) and mushrooms (especially if they are sundried).
Vitamin D is a fat or oil-soluble vitamin that has receptors in the brain's neuronal and glial cells.
However, by age 50, the rate of bone loss tends to be higher than the rate of bone growth, so it's important to get enough bone-building calcium and
vitamin D in your diet.
Vitamin D acts on
vitamin D receptors (VDR) in target cells, where it forms heterodimers with the retinoid X receptor (RXR), which activate
vitamin D target genes.
Majority of patients, 80.2% (142) said they prefer oral tablet in preference to injectable ampule in oral form if given choice while prescribing
Vitamin D. Moreover 66.7% (64) doctors prefer to prescribe tablet form of
Vitamin D instead of injection as oral form for
vitamin D deficiency among their patients.
VDD can exacerbate NAFLD at least in part through an inflammatory-mediated pathway, given how
vitamin D mediates its intracellular signals via the
vitamin D receptor (VDR), which is constitutively expressed in the liver [6].
Another important consideration in this case is the role of
vitamin D in cutaneous disorders of hypopigmentation.
Pakistan is a sun drenched country where the inhabitants are supposed to have enough sunlight exposure to maintain adequate
Vitamin D level.