Thalassemia

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Related to a-thalassemia: Alpha Thalassemia, Thalassaemia minor

thalassemia

[‚thal·ə′sē·mē·ə]
(medicine)
A hereditary form of hemolytic anemia resulting from a defective synthesis of hemoglobin: thalassemia major is the homozygous state accompanied by clinical illness, and thalassemia minor is the heterozygous state and may not have evident clinical manifestations. Also known as Mediterranean anemia.

Thalassemia

 

(also thalassanemia), a familial hemolytic anemia, first detected in 1925 among inhabitants of the Mediterranean region. Thalassemia is caused by disturbances in hemoglobin synthesis.

References in periodicals archive ?
The samples were frozen at -20 [degrees]C and transported to The Netherlands in dry ice for the subsequent identification of cases with a-thalassemia types 1 and 2 in the Central Laboratory for Hematology of the Groningen University Hospital by molecular biological methods.
Other considerations are the prevalence of a-thalassemia in the study population and the required information gain.
2] by CIEF needs to be established, particularly the lower limit for normal values, because the diagnosis of minor a-thalassemia is characterized by a low Hb [A.