absolute configuration


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absolute configuration

[′ab·sə‚lüt kən‚fig·yə′rā·shən]
(organic chemistry)
The three-dimensional arrangement of substituents around a chiral center in a molecule. Also known as absolute stereochemistry.
References in periodicals archive ?
In order to identify compound 1 unequivocally, its absolute configuration was investigated by circular dichroism.
3 ELECTRONIC CD OF BENZENE AND OTHER AROMATIC CHROMOPHORES FOR DETERMINATION OF ABSOLUTE CONFIGURATION
Twenty-five chapters start off with a historical overview and then address such topics as electronic CD of benzene and other aromatic chromophores for determination of absolute configuration, electronic circular dichroism of supramolecular systems, protein-nucleic acid interactions, carbohydrates and glycoconjugates, and drug discovery.
Ten chapters discuss stereochemistry of molecules in inclusion crystals, torsional motion of Stilbene-type molecules in crystals, supramolecular networks of porphyrins, homo- and heterochirality in crystals, supramolecular synthesis of one-dimensional chains and two-dimensional layer in hydrogen bond networks of ureas and two-pyrimidinones, chiral auxiliaries powerful for both enantiomer resolution and determination of absolute configuration by x-ray crystallography, stereoselective thermal solid-state reactions, and other topics.
Though the X8 PROSPECTOR is primarily targeted towards crystal screening it features flexible, user-friendly software which allows it also to be used for other applications, such as absolute configuration of light-atom molecules and protein structure determination.