acanthosis

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acanthosis

[a‚kan′thō·səs]
(medicine)
Any thickening of the prickle-cell layer of the epidermis; associated with many skin diseases.
References in periodicals archive ?
Hyperinsulinemia and acanthosis nigricans in African Americans [see comments] Journal of National Medical Association, 89(8), 523-7.
Characterization of groups of hyperandrogenic women with acanthosis nigricans, impaired glucose tolerance, and or hyperinsulinemia.
Although previous studies have found acanthosis nigricans to be a marker for prediabetes, Dr.
Hud JA Jr, Cohen JB, Wagner JM, Cruz PD Jr: Prevalence and significance of acanthosis nigricans in an adult obese population.
The study identified 24 females aged 9-19 years who were diagnosed with PCOS between 2007 and 2009 using the Rotterdam criteria: 71% had acanthosis nigricans, 75% had a family history of type 2 diabetes mellitus, 71% had a family history of cardiovascular disease, and 87% had body mass index (BMI) greater than 26 kg/[m.
Clinical, biochemical and ovarian morphologic features in women with acanthosis nigricans and masculinization.
The clinical examination was significant for widespread acanthosis nigricans and mild lipomas, as was the cardiac examination.
DIAGNOSIS: Acanthosis nigricans (Figure 1) and necrobiosis lipoidica diabeticorum (NLD) (Figure 2), which are cutaneous manifestations of diabetes mellitus.
Signs of NAFLD/NASH may include: BMI >30; insulin resistance signs such as acanthosis nigricans, skin tags, waist measurement, hypertension, high triglycerides; abdominal fat; hepatomegaly; splenomegaly; signs of cirrhosis such as spider angiomas, esophageal varices, gynecomastia, ascites, jaundice.
Skin lesions include increased skin tags and a condition called acanthosis nigricans - a darkening and thickening of the skin especially in fold areas such as the neckline and axilla.
Three-fourths of the patients had acne, nearly all had hirsutism, and more than half (57%) had acanthosis nigricans, signaling insulin resistance.
2 Once a major criterion is met, the presence of any 2 of the following warrants blood glucose level screening: (1) family history of type 2 diabetes in first-degree or second-degree relative; (2) Native American, African American, Latino, Asian American, or Pacific Islander ethnicities; (3) presence of acanthosis nigricans, hypertension, dyslipidemia, or polycystic ovary syndrome.