acellular vaccine


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acellular vaccine

[¦ā¦sel·yü·lər ‚vak′sēn]
(immunology)
A vaccine consisting of one or more parts of an infectious agent, rather than the whole cell.
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References in periodicals archive ?
The acellular vaccine does protect infants when given in the first years of life; it just doesn't protect long enough.
Although the relative reduction in incidence of pertussis among adolescents aged 11-12 years demonstrates immediate vaccine effectiveness, the increasing number of cases in adolescents aged 13-14 years in both Washington and the United States suggests immunity wanes after Tdap vaccination in those adolescents fully vaccinated with acellular vaccines during childhood (5).
Currently, two types of vaccines including whole cell and acellular vaccines are being used worldwide.
These reactions are substantially lower with the new acellular vaccines ("Pertussis vaccination", 1997).
Acellular vaccine (DtaP) may be used if the child is 15 months old or older and has had three prior doses of whole-cell DTP.
Amplification of the promoter region (ptxP) and ptxA was also unsuccessful during multilocus sequence typing targeting acellular vaccine component genes ptxA, ptxP, prn, and fim3 (8).
In each, the acellular vaccine seemed to impart protection and had few side effects.
The acellular vaccine has purified portions of the bacteria.
Forty-six infants had received no pertussis acellular vaccine, and 11 had received 1 dose.
pertussis cases, which began in 2005 and then spiked even higher in 2010, implicated the acellular vaccine as the cause.
Walther says, however, that this change to the so-called acellular vaccine is not immediately apparent to parents looking for safety information on the Internet.
Additional information about the immunogenicity and safety of a fifth dose following four previous doses of the same acellular vaccine is being collected and should be available before infants started on this new schedule are aged 4-6 years and require a fifth dose.