acellular vaccine


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acellular vaccine

[¦ā¦sel·yü·lər ‚vak′sēn]
(immunology)
A vaccine consisting of one or more parts of an infectious agent, rather than the whole cell.
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Two acellular vaccines are available in the United States, but only for children who are at least a year old.
The efficacy and safety of acellular vaccines were well established in the trials, which were conducted in Italy and Sweden and together enrolled more than 25,000 children.
In research separate from the Erlangen study announced today, clinical trials conducted in Italy and Sweden demonstrated that acellular vaccines appeared to be effective in protecting infants against pertussis.
The acellular vaccine does protect infants when given in the first years of life; it just doesn't protect long enough.
But the FDA has spotted no red flags from Japan, where toddlers have received acellular vaccine - the same one Connaught buys from Japan to put into Tripedia - since 1981 and infants since 1993.
In each, the acellular vaccine seemed to impart protection and had few side effects.
By the late 1990s, the United States had switched from whole-cell to acellular vaccines for all five recommended infant and childhood doses.
1)(2) This acellular vaccine has a safety profile with significantly milder and less frequent adverse events than its whole-cell counterpart.
PHILADELPHIA, July 13 /PRNewswire/ -- SmithKline Beecham (SB) (NYSE: SBE) today issued the following statement in response to disclosure by the National Institute of Allergy and Infectious Diseases (NIAID) of clinical data demonstrating that new, acellular vaccines are highly effective in preventing pertussis (whooping cough):
The development of a pertussis booster vaccine for use from adolescence through adulthood was not possible before the advent of acellular vaccines in the mid-1990s.
While whole-cell pertussis vaccines have saved tens of thousands of lives and have long been the cornerstone of childhood immunization programs in the United States, acellular vaccines promise to become the new gold standard in pertussis immunization" stated Dr.
The new, so-called acellular vaccines rely on the pertussis proteins, rather than a whole bacterium, to spark immunity and are therefore thought to be safer.