The effects of huperzine A, an acetylcholinesterase inhibitor
, on the enhancement of memory in mice, rats and monkeys.
775 [micro]M) as acetylcholinesterase inhibitor
in comparison with physostigmine (6.
Chemical and pharmacological characterization of galanthamine, and acetylcholinesterase inhibitor
, and its derivates.
The study was conducted in patients suffering from moderate Alzheimer's disease, with Lu AE58054 administered as an add-on to donepezil, a commonly used acetylcholinesterase inhibitor
Rivastigmine a brain-region selective acetylcholinesterase inhibitor
for treating Alzheimer's disease: review and current status.
Patients could be enrolled if they were already on stable treatment with an acetylcholinesterase inhibitor
, and about 70% of the patients fell in this category, said Dr.
Results from prior case series and small, open-label studies had suggested that treatment with rivastigmine might help patients with Parkinson's disease-associated dementia, but this was the first large, randomized controlled study to prove the efficacy of any acetylcholinesterase inhibitor
for this form of dementia, Murat Emre, M.
The trial included patients taking acetylcholinesterase inhibitor
(AChEI) treatments (donepezil and rivastigmine) as well as patients not taking AChEIs.
In a study of 202 patients, those who continued treatment with the acetylcholinesterase inhibitor
donepezil had significant improvements in their scores on the Neuropsychiatric Inventory, even when their scores on the Mini-Mental State Examination (MMSE) were stagnant or had declined.
In the UK and Ireland, Shire markets REMINYL(R) (galantamine hydrobromide) and REMINYL XL(R) (galantamine hydrobromide) an acetylcholinesterase inhibitor
that is licensed for symptomatic the treatment of mild and moderately severe dementia of the Alzheimer's type.
The double-blind, randomized trial is the first to examine the effect of the N-methyl-D-aspartate (NMDA) receptor antagonist memantine and the acetylcholinesterase inhibitor
donepezil against donepezil monotherapy, said Dr.
In the UK and Ireland, Shire markets REMINYL(R) (galantamine hydrobromide) and REMINYL XL(R) (galantamine hydrobromide), an acetylcholinesterase inhibitor
that is licensed for the treatment of mild and moderate dementia of the Alzheimer's type.