Megacolon(redirected from acquired megacolon)
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in man, enlargement of part or all of the colon.
Megacolon usually originates with congenital immaturity of the colon’s innervation apparatus. The clinical course of the condition is characterized by persistent constipation beginning in the first years (sometimes in the first months) of life. This, the most common form of megacolon, is called Hirschsprung’s disease. In adults, megacolon may be caused by the presence of mechanical obstructions (tumor, cicatricial stenosis). Treatment is surgical.