acrosin


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acrosin

[′ak·rə·sin]
(biochemistry)
A proteolytic enzyme located in the acrosome of a spermatozoon; thought to be involved in penetration of the egg.
References in periodicals archive ?
Cryopreservation causes permanent functional damage to sperm viability that can be explained partially by the reduction in the percentage of normal intact acrosomes and in total acrosin activity.
The inhibition of acrosin is similar to that of trypsin (3).
Agarwal, "Relationship between acrosin activity of human spermatozoa and oxidative stress," Asian Journal of Andrology, vol.
Several methods have been developed such as cervical mucus penetration, oocyte penetration assay, and measurement of acrosin activity (World Health Organization, 1992).
In the Ap and N-9 treated groups the number of acrosome reacted cells were found to be high and it also caused agglutination of the sperms indicating the loss of intactness of the plasma membrane which was further supported by the significant reduction in the activity of membrane bound 5' nucleotidase and acrosin enzyme.
Furthermore change of biochemical factors have been recognized during cryopreservation, including depletion of amino acids and lipoproteins, release of glutamic-oxaloacetic transaminase (GOT), decrease in phosphatase activity, decrease in loosely bound cholesterol protein, inactivation of acrosin enzyme and hyaluronidase, prostaglandins diminution, increase in sodium, decrease in potassium content, reduction of ATP and ADP synthesis and decrease in acrosomal proteolytic activity [2].
The contents of the acrosome include proteolytic enzymes such acrosin.
Acrosin is one of the principal components in the acrosome, has trypsin-like activity and is secreted after the Acrosome Reaction (RA).
The effect of semen antisperm antibody on human sperm acrosin activity].
Acrosin accelerates the dispersal of sperm acrosomal proteins during acrosome reaction.