acrosin


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acrosin

[′ak·rə·sin]
(biochemistry)
A proteolytic enzyme located in the acrosome of a spermatozoon; thought to be involved in penetration of the egg.
References in periodicals archive ?
Effect of abstinence on sperm acrosin, hypoosmotic swelling, and other semen variables.
Several methods have been developed such as cervical mucus penetration, oocyte penetration assay, and measurement of acrosin activity (World Health Organization, 1992).
In the Ap and N-9 treated groups the number of acrosome reacted cells were found to be high and it also caused agglutination of the sperms indicating the loss of intactness of the plasma membrane which was further supported by the significant reduction in the activity of membrane bound 5' nucleotidase and acrosin enzyme.
Furthermore change of biochemical factors have been recognized during cryopreservation, including depletion of amino acids and lipoproteins, release of glutamic-oxaloacetic transaminase (GOT), decrease in phosphatase activity, decrease in loosely bound cholesterol protein, inactivation of acrosin enzyme and hyaluronidase, prostaglandins diminution, increase in sodium, decrease in potassium content, reduction of ATP and ADP synthesis and decrease in acrosomal proteolytic activity [2].
The effect of semen antisperm antibody on human sperm acrosin activity].
Acrosin accelerates the dispersal of sperm acrosomal proteins during acrosome reaction.
Our observation of a positive association with sperm DNA damage, as measured by Tail%, may also be consistent with previous reports that BP may be a suitable vaginal contraceptive because of its ability to inhibit acrosin (an enzyme that aids sperm penetration into the oocyte during the fertilization process), most likely by damaging the sperm membrane (Song et al.