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actinomycin
(redirected from actinomycin D)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.04 sec.
actinomycin (ăk'tənōmī`sən), any one of a group of antibiotics antibiotic, any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms.

Types of Antibiotics


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 produced by bacteria of the genus Streptomyces. Actinomycin was the first antibiotic reported to be able to halt cancer; however, it is not widely used to treat cancers because it is highly toxic to humans, interfering with the genetic material of cells. It is mainly used as an investigative tool in cell biology.


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(7) The chemotherapeutic element of the IRS IV protocol is significantly different from its predecessors in that the newer agents etoposide, ifosfamide, and melphalan have been added to the standard treatment with vincristine, actinomycin D, and cyclophosphamide.
[25] According to Tefft et al,[26] the use of drugs such as actinomycin D, Adriamycin, and cyclophosphamide to enhance the effects of radiation has resulted in damaged bone.
Thus even with prior exposure of the cells to the toxic chemotherapeutic drug actinomycin D, the cells did not die.
 
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