acute-phase protein


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acute-phase protein

[ə¦kyüt ¦fāz ′prō‚tēn]
(immunology)
Any of a group of proteins that are produced by the liver and appear in the blood in increased amounts shortly after the onset of infection or tissue damage; they include C-reactive protein, fibrinogen, proteolytic enzyme inhibitors, and transferrin.
References in periodicals archive ?
In the current study, detection of anti-Aspergillus antibodies, Aspergillus antigen, and Aspergillus toxin (fumigaclavine A), protein electrophoresis and measurement of acute-phase protein concentrations were performed on serum of 18 adult and plasma of 21 juvenile gyr-saker hybrid falcons (Falco rusticolus X Falco cherrug).
The FebriDx test combines the interpretation of both Myxovirus Resistance Protein A (MxA) C an interferon derivative that becomes elevated in the presence of acute viral infection, and C-reactive Protein (CRP) C an acute-phase protein that is elevated in the presence of bacterial infection.
Overproduction of interleukin-6 has been linked to the principal mediator of the acute-phase protein responsible for symptoms such as fever, anemia, and arthralgia experienced by patients with cardiac myxomas, and raised serum levels may become undetectable after resection of the neoplasm (2).
Serum amyloid A: an acute-phase protein involved in tumour pathogenesis.
CRP is an acute-phase protein produced by the liver.
Classification of systemic amyloidosis AL (light-chain immunoglobulin) Plasma-cell/immunocyte dyscrasia Multiple myeloma AA (serum protein A) Acute-phase protein produced in response to inflammation Rheumatoid arthritis, inflammatory bowel disease, osteomyelitis, tuberculosis, familial Mediterranean fever Gastric carcinoma, renal cell carcinoma, Hodgkin's disease A[beta]2M ([[beta].
Acute-phase protein synthesis in human hepatoma cells: differential regulation of serum amyloid A (SAA) and haptoglobin by interleukin-1 and interleukin-6.
It becomes even more concentrated in the blood of chickens that are fighting infections, turning out to be a major acute-phase protein (APP).
1,3) During ongoing stimulation (chronic infection), positive acute-phase protein levels remain high compared with normal values and can be used for diagnostic purposes.
Hp is a positive acute-phase protein and is characterized by molecular heterogeneity with 3 major phenotypes: Hp 1-1, Hp 2-2, and the heterozygous Hp 2-1 (3).
Among them, an acute-phase protein, SAA, was substantially increased in 44 sera from 24 SARS patients, in contrast to 72 sera from 51 control patients with different viral or bacterial infections.