adaptor protein


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adaptor protein

[ə′dap·tər ‚prō‚tēn]
(cell and molecular biology)
A specialized protein that links protein components of the signaling pathway, thereby aiding intracellular signal transduction.
References in periodicals archive ?
Suppressor of cytokine signaling (SOCS) 5 utilises distinct domains for regulation of J AK1 and interaction with the adaptor protein Shc-1.
The adaptor protein Growth Receptor Bound protein-2 (Grb-2) is essential to cancer cell signaling because it is utilized by oncogenic tyrosine kinases to induce cancer progression.
Tumour protein D52 is a multi-functional adaptor protein that influences numerous cellular processes.
Ifso, CRP might then operate as a kind of fluid-phase adaptor protein, with each of its 2 faces capable of binding to their own unique ligand/receptor pair.
Death initiating signaling complex (DISC) is formed which contains an adaptor protein called FADD (Fas associated death domain) and procaspases-8.
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
IMX942 is a small, proprietary, fully synthetic peptide that binds to an intracellular adaptor protein and modifies the signaling network downstream of TLR, TNF, and IL-1 receptors.
These data indicate that TOR is an adaptor protein interacting with TOTs at one end and multiple components of the vesicle trafficking apparatus at the other end.
Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88.
ctn), the adaptor protein Gab 1, and the HGF/SF receptor Met.
Grb-2 is an adaptor protein that acts as a critical linker between growth factor receptors and the RAS pathway, a pathway commonly activated in cancer.
The Src-like adaptor protein (SLAP) is a negative regulator of T-cell antigen receptor signaling (19) and also regulates B-cell antigen receptor concentrations and signal strength during lymphocyte development (20).
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