adenosine monophosphate


Also found in: Dictionary, Thesaurus, Medical, Acronyms, Wikipedia.
Related to adenosine monophosphate: guanosine monophosphate, Cyclic adenosine monophosphate

adenosine monophosphate

(AMP) (ədĕn`əsēn mŏn'əfŏs`fāt), organic compound composed of an adenineadenine
, organic base of the purine family. Adenine combines with the sugar ribose to form adenosine, which in turn can be bonded with from one to three phosphoric acid units, yielding the three nucleotides adenosine monophosphate, adenosine diphosphate, and adenosine
..... Click the link for more information.
 base, the sugar riboseribose
, monosaccharide carbohydrate of universal distribution in living tissue, found in ribonucleic acid (RNA; see nucleic acid), free nucleotides, and various coenzymes.
..... Click the link for more information.
, and one phosphate unit. AMP is one of the possible products of the hydrolysis of adenosine triphosphateadenosine triphosphate
(ATP) , organic compound composed of adenine, the sugar ribose, and three phosphate groups. ATP serves as the major energy source within the cell to drive a number of biological processes such as photosynthesis, muscle contraction, and the synthesis of
..... Click the link for more information.
 (ATP) and is therefore important in the transfer of chemical energy during anabolism. Cyclic AMP, a very close structural relative of AMP containing an additional ester linkage between the phosphate and ribose units, can act as a secondary messenger for several hormones. It also plays a role in the transcription of some genes (see nucleic acidnucleic acid,
any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis.
..... Click the link for more information.
).

adenosine monophosphate

[ə¦den·ə‚sēn ′mä·nō′fäs·fāt]
(biochemistry)
References in periodicals archive ?
4] PTHrP seems to play an important role in HM,[1,4-6] with characteristic clinical findings such as hypercalcemia, hypophosphatemia, reduction in %TRP, and an increase of urinary cyclic adenosine monophosphate.
AC promotes the formation of a compound called cyclic adenosine monophosphate (cAMP), which is involved in numerous regulatory and signaling pathways in the cell.
Most drugs designed to act on AMPK do so by increasing levels of adenosine monophosphate (AMP) and adenosine diphosphate (ADP).
Although metformin is often described as an insulin sensitizer because it reduces hyperinsulinemia in insulin-resistant patients, he and his colleagues have shown that it acts as a growth inhibitor in human epithelial cells, including breast cancer cells, by activating the adenosine monophosphate kinase pathway (Cancer Res.
The fourth treatment, theophylline, a phosphodiesterase inhibitor that prevents the breakdown of cyclic adenosine monophosphate (the second messenger produced by adenylyl cyclase), was the only agent that restored cell signaling to normal or supranormal levels but did so at further cost to cell replication.
While it is true that caffeine is an adenosine receptor antagonist, it also increases cyclic adenosine monophosphate, (cAMP) which has antiproliferative and immunosuppressive effects.
Linguagen Corporation, a taste technology company based in Cranford, NJ, recently received a letter from FDA indicating that the agency does not have any questions regarding the generally recognized as safe (GRAS) status of its bitter blocker adenosine monophosphate (AMP).
The new theophylline-related drugs are phosphodiesterase 4 (PDE4) inhibitors that target cyclic adenosine monophosphate and prevent its breakdown.

Full browser ?