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adenosine triphosphate

   Also found in: Dictionary/thesaurus, Medical, Financial, Acronyms, Wikipedia, Hutchinson 0.04 sec.
adenosine triphosphate (ATP) (ədĕn`əsēn trī'fŏs`fāt), organic compound composed of adenine adenine (ăd`ənĭn, –nīn, –nēn), organic base of the purine family.
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, the sugar ribose ribose (rī`bōs), monosaccharide carbohydrate of universal distribution in living tissue, found in ribonucleic acid (RNA; see nucleic
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, and three phosphate groups. ATP serves as the major energy source within the cell to drive a number of biological processes such as photosynthesis, muscle contraction, and the synthesis of proteins. It is broken down by hydrolysis to yield adenosine diphosphate (ADP), inorganic phosphorus, and energy. ADP can be further broken down to yield adenosine monophosphate adenosine monophosphate (AMP) (ədĕn`əsēn mŏn'əfŏs`fāt)
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 (AMP), additional phosphorus, and more energy. When the phosphorus and energy are immediately used to drive other reactions, such as the synthesis of uridine diphosphate (UDP), an RNA precursor, from uridine monophosphate (UMP), the pair of reactions are said to be coupled. New ATP is produced from AMP using the energy released from the breakdown of fuel molecules, such as fats and sugars.

Extracellularly, ATP has been found to act as a neurotransmitter neurotransmitter, chemical that transmits information across the junction ( synapse ) that separates one nerve cell (neuron) from another nerve cell or a muscle. Neurotransmitters are stored in the nerve cell's bulbous end (axon).
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. ATP receptors are widespread through the body. On its own it is known to have effects in the arteries, intestines, lungs, and bladder. It is also often released in tandem with other neurotransmitters, perhaps to add chemical stability. See phosphorylation phosphorylation, chemical process in which a phosphate group is added to an organic molecule. In living cells phosphorylation is associated with respiration , which takes place in the cell's mitochondria, and photosynthesis, which takes place in the chloroplasts.
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Basically, this system draws upon adenosine triphosphate (ATP) and phosphocreatine (PC)--which are both stored in the muscles--as the primary fuels.
Their system searches for different cellular materials: bacterial genes, components of bacterial cell walls, the energy-storing molecule called adenosine triphosphate (ATP), and various proteins.
For example, in one study published in the July 2004 issue of Toxicological Sciences, data from microarrays and traditional toxicity tests confirmed previous results from other labs showing that toxic doses of acetaminophen deplete adenosine triphosphate (ATP; molecules that store cellular energy) and damage mitochondria, the organelles that produce ATP.
 
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