All of the previously reported cases of adenosquamous carcinoma
of the nose and paranasal sinuses involved large, extensive, and destructive tumors that required aggressive surgery along with chemotherapy and radiotherapy.
As skin cancers go, adenosquamous carcinoma
(ASC) is somewhat newly recognized and uncommon, said Dr.
44,45,62,66) If TTF-1 reactivity is present in one population of tumor cells and another population is positive for squamous markers, this may raise the possibility of adenosquamous carcinoma
, although this diagnosis can only be made based on a resection specimen.
48) Adenosquamous carcinoma
has been shown to harbor a spectrum of EGFR/KRAS mutations similar to that of adenocarcinoma in Asian patients.
One case was a mucoepidermoid carcinoma, and one was an adenosquamous carcinoma
Attempts to force" cases into one of those WHO categories that may only be reliably assigned on surgically resected specimens (large cell and sarcomatoid carcinomas, adenosquamous carcinoma
, some carcinoid tumors) led to many publications describing the inaccuracy of pathologic classification of lung cancer in small samples.
Polypoid adenosquamous carcinoma
of the esophagus with prominent spindle cells: Report of a case with immunohistochemical and ultrastructural studies.
Several histologic variants of pancreatic cancer have been described, which include adenosquamous carcinoma
, colloid carcinoma, medullary carcinoma, signet ring cell carcinoma, undifferentiated carcinoma, and undifferentiated carcinoma with osteoclast-like giant cells.
77-79) A recent study (80) that carefully excluded mucosally based adenosquamous carcinoma
(which is a mimicker of high-grade MEC) showed higher rates of translocation positivity in high-grade MEC.
Other histologic subtypes include adenosquamous carcinoma
, squamous cell carcinoma, intestinaltype adenocarcinoma, mucinous carcinoma, clear cell carcinoma, signet ring carcinoma, undifferentiated carcinoma, lymphoepithelial-like carcinoma, and small cell carcinoma.
Squamous cell carcinoma is the most common histologic type of carcinoma (Figure 9, A), followed by adenocarcinoma (Figure 9, B) and adenosquamous carcinoma
Surface adenosquamous carcinoma
of the penis: a report of three cases.