adherens junction


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adherens junction

[ad′hir·enz jəŋk·shən]
(cell and molecular biology)
An integrin-mediated anchoring junction that connects the cytoskeleton (actin filaments) of a cell to the extracellular matrix or to the cytoskeleton of surrounding cells.
References in periodicals archive ?
Adherens Junction Targeting In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them.
Disruption of these adherens junction proteins or the actomyosin network that supports them either prevented the formation of the bi-layer, or caused a loss of pre-formed bi-layers.
Deconvolution combined with digital celocalization analysis to study the spatial distribution of tight and adherens junction proteins.
Regulation of Sertoli-germ cell adherens junction dynamics in the testis via the nitric oxide synthase (NOS)/cGMP/protein kinase G (PRKG)/[beta]-catenin (CATNB) signaling pathway: An in vitro and in vivo study," Biology of Reproduction 73(3): 458-471.
Protein kinases and adherens junction dynamics in the seminiferous epithelium of the rat testis," Journal of Cellular Physiology 202(2): 344-360.
Ectoplasmic specialization, a testis-specific cell-cell actin-based adherens junction type: Is this a potential target for male contraceptive development?
Fer kinase/Fer T and adherens junction dynamics in the testis: An in vitro and in vivo study," Biology of Reproduction 69(2): 656-672.
These protective cells (human newborn foreskin shown) can exist as sheets of tissue that are held tightly together by several structures including adherens junctions (green, blue shows cell nuclei).
Nachyline stimulates the formation of adherens junctions, boosts keratinocytes differentiation, reinforces the cohesion and stratification of epidermis and contributes to the organization of the stratum comeum, according to Silk.
GI mucosal barrier integrity is maintained by junctional complexes between epithelial cells including tight junctions, desmosomes and adherens junctions [36-38].
Among the topics are cadherins, adherens junctions and desmosomes, integrins and focal contacts, receptor tyrosine phosphatases, Notch and Slit-Robo signaling, adhesive binding to collagen and fibrillin, and complex adhesive mechanisms involved in leukocyte migration and malaria.
Adjudinmediated junction restructuring in the seminiferous epithelium leads to displacement of soruble guanylate cyclase from adherens junctions," Journal of Cellular Physiology 208(1): 175-187.