alpha receptor

(redirected from adrenergic receptor)
Also found in: Dictionary, Thesaurus, Medical, Legal, Acronyms, Wikipedia.
Related to adrenergic receptor: cholinergic receptor

alpha receptor

[¦al·fə ri¦sep·tər]
(cell and molecular biology)
Any of a group of receptors on cell membranes that are thought to be associated with vasoconstriction, relaxation of intestinal muscle, and contraction of the nictitating membrane, iris dilator muscle, smooth muscle of the spleen, and muscular layer of the uterine wall. Also called alpha-adrenergic receptor.
References in periodicals archive ?
Beta1 adrenergic receptor polymorphisms Arg389Gly and Ser49Gly in the Amerindian and Mestizo populations of Mexico.
In the case of Gencaro, in this review of study data, adrenergic receptor combinatorial pharmacogenetics appear to identify a substantial subpopulation of patients in the study, approximately 45-50% of the total, in which responses appear to exceed outcomes reported for other studies with other beta-blockers in U.
The use of adrenergic receptors as both drug targets, that elicit specific therapeutic effects, and predictors of side effects, that could occur when acted upon by drugs that work through other primary sites of action, is very valuable in drug discovery programs.
Mullinix, PhD, chairman, president and chief executive officer of Synaptic commented, "I am pleased that PRI has asked for licenses to our alpha-1 adrenergic receptor and benign prostatic hypertrophy patent estate.
A2A and beta-2 adrenergic receptor agonists were shown to be highly synergistic and selective agents providing enhanced glucocorticoid activity in B-cell malignancies.
Beginning in March 2000, Synaptic started making available nonexclusive licenses to those companies in need of Synaptic's portfolio of patents on the alpha adrenergic receptors for drug discovery.
The degree of norepinephrine lowering by bucindolol is under genetic control by alpha-2C 322-325 Insertion/Deletion adrenergic receptor polymorphisms (Circulation: Heart Failure 3:21-28 2010).
2] adrenergic receptor (AR) activation by epinephrine (EPI) inhibits epileptiform activity in the mouse hippocampal CA3 region.
To date, the T4-L method has been successfully applied to solve at least nine novelGPCR structures, including the beta 2 adrenergic receptor, the D3 dopamine receptor, the CXCR4 receptor, the H1 histamine receptor, the S1P1 receptor and the A2A adenosine receptor, which have been reported in Science and Nature.
The key classes of mechanism of action include acetylcholine antagonists/blockers, muscarinic receptor antagonists, beta-3 adrenoceptor antagonists, calcium influx inhibitors and intracellular calcium modulators, nonpeptide d-receptor agonists, neuronal serotonin and norepinephrine reuptake inhibitors, vanilloid receptor agonists, beta-3 adrenergic receptor agonists, noradrenaline reuptake inhibitors and NK1 receptor antagonists.

Full browser ?