agonist


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Related to agonist: Agonist muscle, Dopamine agonist

agonist

[′ag·ə‚nist]
(biochemistry)
A chemical substance that can combine with a cell receptor and cause a reaction or create an active site.
(physiology)
A contracting muscle that is resisted or counteracted by another muscle, called an antagonist, with which it is paired.
References in periodicals archive ?
Lycera's synthetic RORgamma agonists bolster the generation of effector immune cells, including Th17 and Tc17 T cells.
Another retrospective study compared a microdose flare-up regimen with a long luteal protocol with decreasing doses of GnRH agonist, and observed higher cancellation rates, lower clinical pregnancies and decreased numbers of oocytes retrieved per cycle with the microdose flare-up regimen (10).
In contrast, the agonist phenotype clustering of NRs showed good concordance with the sequence clustering results because cytotoxicity interference was minimal in the agonist (gain of signal) mode assays and binding to the LBD is probably necessary for a compound to activate an NR.
Adolor has two lead product candidates in development: Entereg[R] (alvimopan) for the management of the gastrointestinal side effects associated with opioid use; and, novel Delta opioid receptor agonists for a variety of pain indications.
The [alpha]-1 agonists, long thought of as drugs of last resort for preventing hypotension associated with neuraxial analgesia in obstetric patients, may not be that bad after all, Dr.
His studies suggest that dopamine agonists and antagonists both block the ill effects of leaving drugs behind.
As with any medicine, beta-2 agonists and theophylline medications for asthma should be administered under the supervision of a physician knowledgeable about their proper use and potential side effects.
longitudinal patient-level claims data that dipeptidyl peptidase (DPP-IV) inhibitors claim a larger share of newly diagnosed type 2 diabetes patients across all three lines of therapy compared to peroxisome-proliferator activated receptor (PPAR)-gamma agonists.
She presented a retrospective study examining treatment utilization patterns among 134,696 commercially insured type 2 diabetes patients placed on a GLP-1 agonist, 202,269 given a DPP-4 inhibitor, and 1,014,630 on other antidiabetic agents.
Although the first glucagon-like peptide-1 receptor (GLP-1R) agonist was already approved in 2005, it was the launch of the once daily GLP-1R agonist Victoza from Novo Nordisk in 2010 which boosted the market size to US$ 1.
METHODS: AhR agonist activity was quantified in sera from dioxin-treated mice, commercial human sources, and polychlorinated biphenyl (PCB)--exposed Faroe Islanders using an AhR-driven reporter cell line.
Consider these risks when prescribing gonadotropin-releasing hormone agonist therapy for men with prostate cancer, and screen for comorbidities, Dr.