agretope


Also found in: Medical.

agretope

[′ag·rə‚tōp]
(immunology)
In antigen presentation, the part of an antigen that interacts with a class II histocompatibility molecule.
References in periodicals archive ?
Xencor's ImmunoFilter tools were developed based on a proprietary immunochemical data set of peptide agretope binding to class II major histocompatibility complex ("MHC") proteins, a key determinant of recognition of antigens by the immune system.
ImmunoFilter technology focuses on MHC binding of protein-derived peptides to predict the presence of class II major histocompatibility complex ("MHC") agretopes in protein sequence.
The HLA-B51 molecule is probably primarily involved in BD development because of the presence of agretopes that have a high affinity for the B51 molecule in some BD-provoking extrinsic factors.