alanine


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Related to alanine: valine, alanine aminotransferase, Beta alanine

alanine

(ăl`ənēn'), organic compound, one of the 20 amino acidsamino acid
, any one of a class of simple organic compounds containing carbon, hydrogen, oxygen, nitrogen, and in certain cases sulfur. These compounds are the building blocks of proteins.
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 commonly found in animal proteins. Only the l-stereoisomer participates in the biosynthesis of proteins (see stereochemistrystereochemistry,
study of the three-dimensional configuration of the atoms that make up a molecule and the ways in which this arrangement affects the physical and chemical properties of the molecule.
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). Its side chain is a nonpolar, hydrophobic methyl group. The low reactivity of the amino acid permits silk, a protein which contains some 30% alanine, to have a simple, elongated structure with few cross-links. This contributes to the desirable features of the fiber-strength, resistance to stretching, and flexibility. Alanine is not essential to the human diet, since it can be synthesized from other cellular metabolites. It was discovered in protein in 1875.

alanine

[′al·ə‚nēn]
(biochemistry)
C3H7NO2 A white, crystalline, nonessential amino acid of the pyruvic acid family.
References in periodicals archive ?
A straightforward approach to assessing the alanine time dependence would be to irradiate a select group of alanine dosimeters and record their response over several years.
More Hepsera-treated patients achieved normalized alanine aminotransferase levels, reductions in hepatitis B DNA to below 400 copies/mL, and HBeAg seronegativity.
Of the remaining 14 patients, 6 had a documented seroconversion but not a documented exposure; the only indication of acute infection in the remaining 8 patients was their elevated serum alanine aminotransferase levels, which ranged from 635 to 1,500 U/L, with no prior signs of liver disease.
Sixty-nine percent (38/55) of patients who received Hepsera for 240 weeks exhibited improvement in liver function, as measured by normalization of serum alanine transferase (ALT) levels.
Liver biochemistry was abnormal with the following values: alkaline phosphatase 513 U/L, alanine aminotransferase 38 U/L, and aspartate aminotransferase 65 U/L.
The group used strong magnetic fields and radio wave pulses to manipulate the nuclear spins of atoms in pencil-size test tubes of liquids, such as a solution of the amino acid alanine.
The patent covers (1) methods for supporting metabolism and transportation of glucose and carbohydrates into skeletal muscle cells by the administration of a therapeutically effective amount of a composition of bio-active compounds extracted from fenugreek seeds, and (2) methods for performing weight management by the administration of a therapeutically effective amount of a composition comprising 4-hydroxyisoleucine and one or more amino acids selected from the group consisting of arginine, aspartate, threonine, serine, glutamate, proline, glycine, alanine, cysteine, valine, methionine, isoleucine, leucine, tryptophan, phenylalanine, ornithine, lysine, histidine, and gamma-aminobutyrate.
6003/14 alanine aminotransferase (alt), reagent for determination of test
Contract awarded for 3613 order code 12560 alanine amino transferase (alt) reagent for determination.
Her liver function tests showed elevated levels of bilirubin, 46 [micro]mol/L; alanine aminotransferase, 2,421 IU/L; and alkaline phosphatase, 200 IU/L.
They successfully replaced the bulk of a small, biologically important protein with an equivalent structure made only of the amino acids isoleucine, lysine, glutamate, alanine, and glycine.
Treatment with Hepsera also resulted in changes in laboratory markers of liver function, as measured by serum levels of alanine aminotransferase (ALT).