alkylate

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alkylate

[′al·kə‚lāt]
(organic chemistry)
A product of the alkylation process in petroleum refining.
References in periodicals archive ?
Three small, nonrandomized studies using historical controls suggest some protective effect in patients getting GnRH before alkylating chemotherapy for Hodgkin's disease and non-Hodgkin's lymphoma.
Alkylating agents are highly reactive chemicals that introduce alkyl groups into biologically active molecules and prevent normal functioning.
He and a team of researchers have developed a way to measure the ability of particular cancer cells to repair the damage done to DNA by a category of commonly utilized anti-cancer drugs that are known as alkylating agents, including nitrosourea and cisplatinin.
Alkylating and non-alkylating compounds interacting with the DNA minor groove.
CHRONOS-2: A Phase III randomized, double-blind, placebo-controlled study of copanlisib in rituximab refractory indolent NHL patients who have previously been treated with rituximab and alkylating agents (NCT02369016)
Group 8 - analogs, alkylating agents nitrogen mustard
Radiotherapy and chemotherapy with alkylating agents (e.
Other therapy combinations significantly associated with high relative risks were abdominal/pelvic radiation and an alkylating agent (7.
The classes of chemical compounds that cause cancer--including alkylating agents, DNA-damaging agents, and toxicants that affect the cell cycle--vary in the mechanisms by which they cause the disease.
Using these and other factors, the retrospective study of more than 9,000 patients provides strong statistical evidence that approximately half of the secondary bone cancers observed can be blamed on radiation therapy or on chemotherapeutic alkylating agents such as the frequently prescribed cyclophosphamide.
PredictMDx for Glioblastoma, MDxHealth's most advanced epigenetic assay is designed to identify newly diagnosed GBM patients most likely to benefit from treatment with alkylating agents.
The study involved drugs called alkylating agents that are widely used to treat a variety of pediatric cancers.