allele frequency

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allele frequency

[ə′lēl ¦frē·kwən·sē]
(genetics)
The fraction of all alleles at a given locus constituted by a particular allele in a population. Also known as gene frequency.
References in periodicals archive ?
Thus knowledge of allelic frequency distribution within a population can be useful in optimizing doses for therapeutic efficacy, identifying potential risk groups for adverse drug reactions and explaining therapeutic failures.
However, major dispersion data estimated for northern Chilean populations could slant the genetic parameters calculated, mainly as a result of a high null allelic frequency and an excess of homozygotes.
2004) reported evidence of positive selection on the derived allele of the functional CYP3A5*3 in non-African populations and significant correlation of its allelic frequency with distance from the equator.
An FVL allelic frequency of about 2% was initially reported in the Dutch population.
The allelic frequency of the kdr gene in the 'S' form was proportionate to the resistant level in the mosquito population.
Meanwhile, we evaluated the effects of minor allelic frequency (MAF) and sample size on LD estimations.
he held the position of Executive Vice President, Genomics and was responsible for the development of a suite of technologies for the discovery, scoring, and determination of allelic frequency of disease-associated SNPs (single nucleotide polymorphisms).
Most of the population loci showed a low, inferred null allelic frequency (Dakin & Avise 2004).
In this group, the allelic frequency for the variant allele of 35991 was 77.
From 1998 to 1999, the frequency of isolates with mutated Pfdhfr codons 51, 59, and 108 decreased (not significantly), and Pfdhps allelic frequency did not differ significantly.
Our studies indicate that the 2004 and 2005 BB populations are genetically similar with some allelic frequency differences.