SUBLIVAC FIX Phleum pratense is an allergen extract
of Phleum pratense pollen for sublingual use.
Attempted treatment with allergen-specific immunotherapy, where a patient received monthly injections with an allergen extract
for three to five years, failed because it could cause anaphylaxis as a side effect.
Despite the difficulties we encountered in aerosolizing whole pollen grains, we chose to use whole pollen grains because they more closely approximate real-life exposure than does allergen extract
Allergen immunotherapy involves administering gradually increasing doses of allergen extract
to induce immune tolerance.
Patients were randomized to receive a once-daily tablet of Ambrosia artemisiifolia (ragweed) allergen extract
at a dose of 6 Amb a 1-U or 12 Amb a 1-U or placebo for approximately 16 weeks prior to and throughout the ragweed pollen season, for a total treatment period of 52 weeks.
According to the Company, RAGWITEK is an allergen extract
indicated as immunotherapy for the treatment of short ragweed pollen-induced allergic rhinitis with or without conjunctivitis confirmed by positive skin test or in vitro testing for pollen-specific IgE antibodies for short ragweed pollen.
SUBLIVAC FIX Birch is an allergen extract
of birch pollen for sublingual use.
Microarray assays require <1 nL of allergen extract
per test, which allows the use of the more expensive allergen extracts
used for SPT in microarray production.
Normally, either a skin prick test is performed by introducing a small amount of the suspected allergen into the skin, or a basic blood test for antibodies to the allergen extract
is carried out.
Mouse airways were exposed to house dust mite allergen extract
to gauge the severity of disease and analyze biochemical responses in airway tissues.
Activated, washed microspheres were suspended in 50 [micro]L of diluted allergen extract
(1:100 in PBS, pH 7.
TSX: PLB) announced today that they have entered into a Canadian development, promotion and distribution agreement for Oralair(TM), Stallergenes' allergen extract
immunotherapy sublingual tablets.