alloantibody


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Related to alloantibody: alloantigen

alloantibody

[¦a·lō¦ant·i‚bäd·ē]
(immunology)
Antibody that reacts with an antigen occurring in a genetically different member of the same species.
References in periodicals archive ?
Initial monitoring is performed by antenatal titrations to determine if the titre of the alloantibody is increasing or is greater than or equal to 16.
Management of a severe transfusional problem in a patient with alloantibody to Kpb (K4).
The transfusion of matched red cell units can prevent alloantibody formation.
The panagglutinating antibody may mask a coexisting alloantibody and place the patient at increased risk for a hemolytic transfusion reaction.
Evaluation of polyethylene terephthalate for ABO and Rh typing and alloantibody screening.
One study of a group of cancer patients showed that approximately 9% formed alloantibodies and that risk of developing alloantibody was 0.
Institutions were asked how many patients (or donors) with the weak D phenotype were also found to have formed an anti-D alloantibody (transfusion or pregnancy related) in the past 12 months.
Clinical and Laboratory Standards Institute (CLSI) has recently published a new document, Detection of HLA-Specific Alloantibody by Flow Cytometry and Solid Phase Assays; Proposed Guideline (I/LA29-P), which describes criteria for optimizing flow cytometry crossmatching and the detection of HLA alloantibody by solid-phase methods in conventional and multiplex platforms.
In most cases, an IgG alloantibody or autoantibody arises in response to the drug or a drug-platelet protein complex.