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alloantibody

   Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
alloantibody [¦a·lō¦ant·i‚bäd·ē]
(immunology)
Antibody that reacts with an antigen occurring in a genetically different member of the same species.


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8 New CLSI guidelines provide optimal methods II CLSI guideline, "Detection of HLA-Specific Alloantibody by Flow Cytometry and Solid Phase Assays; Approved Guideline," describes criteria for optimizing flow cytometry cross matching and the detection of human leukocyte antigen (HLA) alloantibody by solid phase methods in conventional and multiplex platforms.
After a short incubation, rabbit serum was added as a source of complement, and the cells that had bound the alloantibody were lysed, making them permeable to the fluorochrome ethidium bromide.
Institutions were asked how many patients (or donors) with the weak D phenotype were also found to have formed an anti-D alloantibody (transfusion or pregnancy related) in the past 12 months.
 
 
 
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