alloantigen


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alloantigen

[¦a·lō¦ant·i·jən]
(immunology)
References in periodicals archive ?
We followed the same protocol reported previously [6], but, instead of performing assessment 1 week after the last treatment, we evaluated tolerance 6 weeks after finishing tolerance induction through alloantigen challenge by intravenous injection of allogeneic Balb/c spleen cells.
To determine whether PD-1/PD-L1 pathway plays a role in UVB-iDC-induced allogeneic tolerance, we employed anti-mouse PDL1 antibodies to block the PD-1 signaling in the mice with long-lasting tolerance during alloantigen challenge.
from the University of New SouthWales (Australia) showed that Th1 and Th2 responses promoted the development of two different pathways of alloantigen specific Tregs in vivo, depending on the cytokine milieu.
It is hoped that immunologic tolerance to certain nonself antigens, such as alloantigens in organ transplants, can be established as stably as natural tolerance to self-constituents.
In view of the high expression of CD89 on monocytes, we aimed to target the HLA monomer towards CD89 for more efficient presentation of this alloantigen.
In organ transplantation CD4 T-cells can recognize HLA alloantigens either after internalization and processing by recipient "antigen presenting cells" (APC, indirect pathway) or directly on donor APCs (direct pathway) [1].
The effect of human platelet alloantigen polymorphisms on the in vitro responsiveness to adrenaline and collagen.
NK cells in CB appear to be similar to those in APB, and these cells may actually have greater proliferative capacity when exposed to alloantigens or exogenous cytokines (8), (18), (21).