allodynia


Also found in: Dictionary, Medical, Wikipedia.

allodynia

[‚a·lə′dī·nē·ə]
(medical)
Painful response to a stimulus that does not normally elicit pain.
References in periodicals archive ?
The clinical and electrophysiological findings of our patient were concordant with probable vasculitic neuropathy Because of the serious neuropathic complaints and allodynia, he clearly ignored other problems related to his neurologic deficits.
As a result, hypersensitivity manifests as both hyperalgesia and allodynia occurs, for which standard analgesic treatments are unsuccessful.
Thermal hyperalgesia and mechanical allodynia were initiated on day 3 after CCI until day 21, peaking on day 7.
All patients presented with sensory or autonomic symptoms, which included disturbance of pinprick sensation and temperature sensation, allodynia, hyperalgesia, numbness, coldness, tightness, burning sensation, tingling sensation, bedsheet intolerance, restless legs, sensation of walking on sand or pebbles, muscle cramps, palpitations, hot flushes, hyper/hypohidrosis, skin discoloration, difficulty in urination, constipation/diarrhea, sexual dysfunction, or sicca syndrome.
20) And, we reported that in naive animals, spinal microglia express a receptor for IFN-[gamm] (IFN-[gamm]R) in a cell-type specific manner and that stimulation of this receptor changes microglia into activated form and produces a long-lasting tactile allodynia.
Reversal of cisplatin-induced mechanical allodynia in the preclinical model was also observed after treatment with the selective HDAC6 inhibitor ricolinostat (ACY-1215) that is currently in clinical trials for cancer treatment.
Brush-evoked allodynia may be a significant negative prognostic factor of SCS treatment outcome after 1 year in chronic CRPS-1 (62).
Other reported symptoms were dizziness, allodynia and neck stiffness.
Physical examination findings included mild edema, allodynia, and hyperalgesia in the bilateral preauricular area and bilateral masseter muscle.
In addition, the bioflavonoids have been reported to suppress COX-2 enzymes though the mechanism of this action is not fully understood [53], and attenuates the cold allodynia as well as hyperalgesia [54].
Patients over the age of 60 more commonly develop postherpetic neuralgia and can experience pain, numbness, dysesthesia, and allodynia.