allopurinol


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Related to allopurinol: gout, colchicine

allopurinol

[‚a·lə′pyür·ə‚nȯl]
(pharmacology)
C5H4ON4 The compound 4-hydroxypyrazolo-3,4-d-pyrimidine; inhibits xanthine oxidase, an enzyme required for uric acid formation.
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These pathological states were ameliorated in some degree by treating with allopurinol and 10mg/kg doses of riparoside B and timosaponin J (Fig.
Probenecid is a uricosuric agent and an alternative to allopurinol.
Additional results from our Phase 2b study evaluating lesinurad in combination with allopurinol in gout patients not adequately responding to allopurinol;
Moreover, this increase in blood pressure could be abrogated by concurrent treatment with allopurinol (Fig.
Some of the recommendations provided are similar, such as treating to a target serum uric acid level, and the 'start low, go slow' approach to allopurinol therapy.
Despite only having launched in the first quarter of this year, Adenuric has already achieved a significant competitive advantage over Allopurinol on most key product attributes which drive physician prescribing of gout therapies.
Allopurinol is the most popular choice among uric acid-lowering drugs in current clinical use for gout management.
Long-term Safety of BCX4208 Added to Allopurinol in the Chronic Management of Gout: Results of a Phase 2 24-week Blinded Safety Extension and Vaccine Challenge Study" concludes that BCX4208 was safe and generally well-tolerated when added to allopurinol.
On the other hand, the dosages for pure compounds and allopurinol assay were 100, 50, 25, 10, 5, 1 [micro]g/ml.
Patients with the combined defect have an inability to convert allopurinol to oxypurinol (Fig.
longitudinal patient-level claims data that on average, recently treated gout patients took allopurinol (Prometheus Laboratories' Zyloprim, generics) for an average of six months before switching to their current therapy.