allosteric transition

(redirected from allosteric change)
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allosteric transition

[¦a·lə¦stir·ik tranz′ish·ən]
(biochemistry)
A reversible exchange of one base pair for another on a protein molecule that alters the properties of the active site and changes the biological activity of the protein.
References in periodicals archive ?
These polyether brevetoxins and a number of synthetic derivatives have had some limited success in dissecting the various molecular allosteric changes thought to occur sequentially during ion channel topographic progression from closed to open to inactivated and back to the closed state.
Allosteric changes can be induced by binding the protein to another protein called a ligand, while the allosteric protein that changes shape is often a receptor.