allosteric site


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Related to allosteric site: competitive inhibition

allosteric site

[¦a·lə¦ster·ik ′sīt]
(biochemistry)
The inactive (or less active) region of an enzyme molecule.
References in periodicals archive ?
The Ii-Key motif from the Ii protein acts at an allosteric site adjacent to the MHC class II antigenic peptide-binding trough to enhance presentation of covalently linked epitopes 200-500 times in vitro.
As part of its presentations, Astex Pharmaceuticals scientists will present on the discovery of the allosteric site using their Pyramid approach and on initial work aimed at validating the anti-viral activity of these first-in-class fragment-derived allosteric inhibitors.