alpha fetoprotein


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alpha fetoprotein

[′al·fə ¦fēd·ō′prō‚tēn]
(immunology)
A serum protein that has become associated with the detection of certain types of cancer and fetal abnormalities. Abbreviated AFP.
References in periodicals archive ?
Between pregnancy biological variability of maternal serum alpha fetoprotein and free beta hCG: implications for Down syndrome screening in subsequent pregnancies.
2 Typical presentation of HCC includes solitary mass in normal or cirrhotic liver with elevated alpha fetoprotein.
5 Moreover, these patients with paraneoplastic syndromes, including hypercalcaemia, usually present at an advanced stage, with high alpha fetoprotein, large tumour volume and have a poor prognosis.
Types of screening covered include maternal serum alpha fetoprotein (AFP), human chorionic gonadotropin (hCG), unconjugated estriol (uE3), acetylcholinesterase (AchE), dimeric inhibin A (DIA), and pregnancy-associated plasma protein A (PAPP-A).
Histologically, the tumor can be difficult to diagnose, although elevated levels of alpha fetoprotein can facilitate its identification.
Special staining demonstrated that only a very few tumor cells were positive for alpha fetoprotein, despite the markedly elevated level of alpha fetoprotein in her serum.
An English study found that measuring human chorionic gonadotrophin was a much better test for detecting the presence of Down's syndrome than methods currently used -- measuring unconjugated estriol and alpha fetoprotein.
The study also emphasizes on the importance of clinical presentation, median age at presentation and evaluation of raised titres of serum alpha fetoprotein levels in hepatoblastoma.
Complete blood count, liver function test, total protein, Albumin/Globulin (A/G) ratio, serum Albumin, HBsAg, anti HCV, alpha fetoprotein, ultrasound guided liver biopsy, ultrasound whole abdomen and/or CTscan Abdomen for size and number of tumour were also done.
A diagnosis of extra gonadal primary yolk sac was made Serum hormone assays were performed including beta-HCG and alpha fetoprotein.
alpha fetoproteins or carcinoembryonic antigens) in these lesions.