alpha helix

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alpha helix

[′al·fə ′hē·liks]
(cell and molecular biology)
A spatial configuration of the polypeptide chains of proteins in which the chain assumes a helical form, 0.54 nanometer in pitch, 3.6 amino acids per turn, presenting the appearance of a hollow cylinder with radiating side groups.
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References in periodicals archive ?
It's the first example of an alpha-helical inhibitor of any protease.
The region of PspA in the cloned fragment includes the entire alpha-helical region of the protein and in some cases some of the proline-rich region, which is C-terminal to the alpha-helical region.
a molecular biologist at the University of California, Berkeley, and his colleagues have used the alpha-helical strands of proteins to engineer a benzene-sensitive switch.
AILERON's Stapled Peptides are synthetically locked, or 'stapled', into an alpha-helical shape with an optimized cross-linking chemistry to mimic the structure found at the interface of many protein-protein interactions.
PSMs are small alpha-helical peptides which have two distinct functions on the immune system, in vitro PSMs can attract neutrophils in the nanomolar range, whereas in the micromolar range they are cytolytic for neutrophils.
Alphabodies are small single chain alpha-helical proteins that are designed by computer modeling, but are inspired by naturally existing polypeptide structures.