relaxes muscles in erectile tissue of the penis, allowing blood to flow in.
Men who can't tolerate any PDE-5 inhibitor or who are among the 20%-30% who don't respond can try Alprostadil
in injection or pellet form.
Trimix is an off-label mixture of three Food and Drug Administration-approved drugs: papaverine, phentolamine, and alprostadil
A system for inserting a pellet of alprostadil
into the urethra is marketed as Muse.
Even more encouraging, especially for men who cannot stand the thought of using a needle, is the recent availability of alprostadil
in the form of a tiny "seed" one places in the urethral opening at the tip of the penis, where it is quickly absorbed.
Apricus Bio incorporated alprostadil
with its NexACT delivery technology, resulting in a rapid and efficient topical delivery of the drug into the penis.
blister 500 mc / 1 ml solution for injection
The company stated the patent covers the combination of alprostadil
and its proprietary NexACT technology and enables the rapid absorption of high concentrations of an active pharmaceutical ingredient at the target site that is designed to enhance the delivery of an active drug to the patient.
M2 PHARMA-November 30, 2010-Dongsheng acquires IP, sales and manufacturing rights to micro-emulsion alprostadil
injection for USD1.
(Alista), manufactured by Vivus Inc.