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1. Pathol any substance that passes into and accumulates within cells, tissues, or organs
2. Pathol a local anaesthetic solution injected into the tissues to cause local anaesthesia



an accumulation in bodily tissues of cellular elements admixed with blood and lymph. Inflammatory and tumorous infiltrates occur most often.

An inflammatory infiltrate consists chiefly of polymorphonuclear leukocytes (suppurative infiltrate), erythrocytes (hemorrhagic infiltrate), lymphoid cells (round cell infiltrate), and histiocytes and plasma cells (histiocyte-plasma cell infiltrate). These infiltrates may be resolved, may liquefy, or may undergo sclerosis and form caverns, abscesses, scars, and so forth.

A tumorous infiltrate consists of tumor cells of different kinds (carcinoma, sarcoma); it is a manifestation of the infiltrating growth of a tumor. When an infiltrate forms, the tissue enlarges, changes color, and becomes harder and sometimes painful. In surgical practice, an infiltrate is an induration that develops in tissues when they become saturated with an anesthetic.


References in periodicals archive ?
The lesions of chronic hydrocarbon aspiration are quite different, presenting with pseudotumours' or crazy paving alveolar infiltrates having negative CT attenuation values (Hounsfield Units <0)(25).
11) When a patient does seek medical attention, the chest x-ray might show a variety of pulmonary parenchymal lesions, including local consolidation (28% of patients), mass-like lesions (23%), diffuse alveolar infiltrates (13%), and cavitary lung lesions (10%).
The criteria include unexplained worsening of dyspnea within a month, hypoxemia, new alveolar infiltrates identified radiologically, and absence of an alternate explanation.
Focal infiltrates, nodules and diffuse alveolar infiltrates are less common findings and were noted in 2 of our patients.
The chest x-ray can show patchy bilateral alveolar infiltrates or diffuse reticular infiltrates.
A diagnosis of DAH should be entertained only when a patient presents with diffuse alveolar infiltrates.
Of note on the chest radiograph were right upper lobe alveolar infiltrates.