rhabdomyosarcoma

(redirected from alveolar rhabdomyosarcoma)
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Related to alveolar rhabdomyosarcoma: embryonal rhabdomyosarcoma

rhabdomyosarcoma

[¦rab·dō‚mī·ō·sär′kō·mə]
(medicine)
A malignant tumor of skeletal muscle in the extremities composed of anaplastic muscle cells. Also known as malignant rhabdomyoma; rhabdomyoblastoma.
References in periodicals archive ?
D, Alveolar rhabdomyosarcoma shows monotonous round cells with an "alveolar" growth pattern and strong myoD1 nuclear expression (E).
Response to "Metastatic alveolar rhabdomyosarcoma with increased serum creatinine kinase MB and cardiac Troponin T and normal cardiac troponin I".
Core biopsies of both tumors revealed similar, round-cell neoplasms that were confirmed to be alveolar rhabdomyosarcomas by immunohistochemical and ultrastructural studies, with positive staining for vimentin, desmin, and muscle specific actin.
Immunohistochemistry was done and it was positive for desmin (figure 3), myogenin and myo D1, thus confirming the diagnosis of alveolar rhabdomyosarcoma.
106) Although rare, Barr and colleagues (107) have documented a true "fusion-negative" subset of alveolar rhabdomyosarcoma, represented by a genetically diverse subset of tumors.
He was nominated for an award after fighting a rare cancerous growth in his testicle, called paratesticular alveolar rhabdomyosarcoma, when he was just 13 months old.
Just three weeks after her eighth birthday in February 2014, Rebecca's family received the devastating news that their daughter's leg swelling had not been caused by a muscle tear but by alveolar rhabdomyosarcoma, a rare type of soft tissue cancer which affects only 60 children each year.
Alveolar rhabdomyosarcoma infiltrating bone marrow at presentation: the value to diagnosis of bone marrow trephine biopsy specimen.
Almost all examples of ES/ PNET and poorly differentiated SS harbored rearrangements of EWSR1 or SYT, respectively, whereas alveolar rhabdomyosarcoma was characterized by rearrangement of FOXO1A (13q14) in only 66% of cases.
Rebecca's family, including dad Paul and mum Tracy, was shocked to be told in February last year that the then-eightyear-old's leg swelling wasn't caused by a muscle tear, as suspected, but by alveolar rhabdomyosarcoma, a cancer so rare only 60 children are diagnosed with it each year.
Rebecca was diagnosed with the rare alveolar rhabdomyosarcoma after being taken to hospital with a swollen leg in February this year.