The amount of amalgam treatment was characterized by the number of amalgam surfaces placed at baseline (i.
Mean urinary mercury concentrations for male and female participants were similar at baseline, but increases after amalgam treatment were larger for females than for males.
The increase in urinary mercury concentrations was positively associated with the amount of amalgam treatment received at baseline and during follow-up (Figure 4).
To our knowledge, this is the first study to describe urinary mercury excretion patterns in children during the longitudinal course of amalgam treatment from childhood through adolescence and to quantify the relationship between amalgam surfaces and urinary mercury concentrations during the course of treatment.
These differences held up after adjustment for creatinine and differences in the amount of amalgam treatment received (Table 2).