amber mutation


Also found in: Medical.

amber mutation

[′am·bər myü′tā·shən]
(genetics)
Alteration of a codon to UAG, one of the three codons that result in premature polypeptide chain termination in all living organism.
References in periodicals archive ?
strains insert an amino acid in response to an amber docon and may restore activity to any altered regulatory gene resulting from an amber mutation.
The only bacteria that survived were those that incorporated an amino acid--either a natural or an introduced one--at the location of the amber mutation.
These bacteria already had an amber mutation in a gene that encodes barnase, a protein that kills bacteria.